MOGAT1

Across TCGA patient cohorts, MOGAT1 mutation is significantly associated with the RNA expression of many other genes, with 263 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible MOGAT1-associated genes across cancer lineages are XAGE1B, MTRES1P1, and HMGN2P26. Each is linked with MOGAT1 in more than 1 cancer types. Because this analysis shows association rather than direction, both MOGAT1-to-partner and partner-to-MOGAT1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, XAGE1B grouped by MOGAT1-low versus MOGAT1-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MOGAT1→partner) and Y-score (partner→MOGAT1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	XAGE1B →	+0.318	+2.501	<.001	.006	3	2
SKCM	MTRES1P1 →	+0.043	+3.265	<.001	.006	3	2
UCEC	HMGN2P26 →	+0.260	+5.299	.001	.006	3	2
COAD	RNU6-389P →	+0.620	+5.017	<.001	.009	3	2
LUSC	MIR1976 →	+0.487	+5.148	<.001	.002	3	2
LUSC	NCOR1P1 →	+1.953	+4.245	<.001	.003	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 263 associations by consensus.

XAGE1B by MOGAT1 expression — SKCM

Explore this box plot interactively →