MOGAT1

Across TCGA pan-cancer cohorts, MOGAT1 RNA differs between tumor and matched normal tissue in 11 of 18 cancer types tested, making tumor–normal expression one of MOGAT1’s most consistent transcriptional readouts.

The strongest signal is observed in lung adenocarcinoma (LUAD), where MOGAT1 RNA is repressed in tumor relative to normal tissue. In most cancer types MOGAT1 is over-expressed in tumor, although a few such as LUAD and LUSC show the opposite, repressed pattern.

LUAD, LUSC, and UCEC are the cancer types where MOGAT1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in MOGAT1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
LUAD	Male	All	−0.819	<.001	9	view →
LUSC	Female	II,III,IV	−0.915	<.001	8	view →
UCEC	All	II,III,IV	+0.928	<.001	6	view →
LIHC	Female	II,III,IV	−0.524	<.001	6	view →
BRCA	All	All	−0.518	<.001	6	view →
KICH	Male	All	−0.492	<.001	6	view →
HNSC	Male	III,IV	−0.101	.009	6	view →
ESCA	All	All	−0.640	.011	2	view →
COAD	All	II,III,IV	+0.122	.022	2	view →
PRAD	All	All	+0.089	.008	2	view →
CHOL	All	All	−0.724	.033	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 11 strongest of 11 lineages.

MOGAT1–LUAD

Open the LUAD breakdown →