MOCS3

Across TCGA patient cohorts, MOCS3 mutation is significantly associated with the RNA expression of many other genes, with 3,764 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible MOCS3-associated genes across cancer lineages are MIR147A, GAGE13, and PCBD1. Each is linked with MOCS3 in more than 2 cancer types. Because this analysis shows association rather than direction, both MOCS3-to-partner and partner-to-MOCS3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR147A grouped by MOCS3-low versus MOCS3-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MOCS3→partner) and Y-score (partner→MOCS3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	MIR147A →	+0.431	+4.156	<.001	.001	3	3
SKCM	GAGE13 →	+0.500	+2.641	<.001	.009	3	2
UCEC	PCBD1 →	+0.569	+2.254	<.001	.005	3	2
SKCM	RNA5SP319 →	+0.240	+3.290	<.001	.001	3	2
SKCM	UST-AS1 →	+0.047	+2.652	<.001	.004	3	2
CESC	RNU6-275P →	+0.215	+4.569	<.001	.005	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,764 associations by consensus.

MIR147A by MOCS3 expression — COAD

Explore this box plot interactively →