MOCS2

Across TCGA patient cohorts, MOCS2 RNA expression is significantly associated with the protein abundance of many other proteins, with 14,254 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible MOCS2-associated proteins across cancer lineages are PTPN7, THEMIS2, and TXNDC5. Each is linked with MOCS2 in more than 4 cancer types. Because this analysis shows association rather than direction, both MOCS2-to-partner and partner-to-MOCS2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, MOCS2 versus PTPN7 in GBM, with a Pearson correlation of -0.45.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (MOCS2→partner) and Y-score (partner→MOCS2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	PTPN7 →	-0.625	-0.446	<.001	<.001	3	5
GBM	THEMIS2 →	-0.628	-0.401	<.001	<.001	3	4
BRCA	TXNDC5 →	-0.513	-0.417	<.001	<.001	3	4
BRCA	UNC13D →	-0.334	-0.506	<.001	<.001	3	4
BRCA	MTX3 →	+0.417	+0.399	<.001	<.001	3	4
GBM	MYO1F →	-0.656	-0.313	<.001	.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,254 associations by consensus.

MOCS2 vs PTPN7 — GBM

Explore this scatter interactively →