MOCS2

mutation — cross-omics
Cross-omicsMUTATION → IMMUNEPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, MOCS2 mutation is significantly associated with the immune_cell of many other genes, with 2 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible MOCS2-associated genes across cancer lineages are Basophils and Endothelial cells. Each is linked with MOCS2 in more than 1 cancer types. Because this analysis shows association rather than direction, both MOCS2-to-partner and partner-to-MOCS2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Basophils grouped by MOCS2-low versus MOCS2-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MOCS2→partner) and Y-score (partner→MOCS2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECBasophils →+0.188+2.000.014.03231
UCECEndothelial cells →-0.038-1.957.028.03211
Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

Basophils by MOCS2 expression — UCEC

Box plot of Basophils in MOCS2-low vs MOCS2-high samples in UCEC.

Explore this box plot interactively →

Exploration