MOCS2

Across TCGA cell cohorts, MOCS2 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,256 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible MOCS2-associated GO terms across cancer lineages are Dihydrofolate metabolic process, Regulation of chromosome separation, and Negative regulation of metaphase/anaphase transition of cell cycle. Each is linked with MOCS2 in more than 10 cancer types. Because this analysis shows association rather than direction, both MOCS2-to-partner and partner-to-MOCS2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Dihydrofolate metabolic process grouped by MOCS2-low versus MOCS2-high in OESOPHAGUS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MOCS2→partner) and Y-score (partner→MOCS2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	Dihydrofolate metabolic process →	+0.180	+1.005	<.001	<.001	3	11
OESOPHAGUS	Regulation of chromosome separation →	+0.135	+0.802	.006	.007	3	10
LIVER	Negative regulation of metaphase/anaphase transition of cell cycle →	+0.149	+0.945	<.001	<.001	3	10
LIVER	Negative regulation of chromosome separation →	+0.149	+0.945	<.001	<.001	3	10
OVARY	Regulation of mitotic sister chromatid separation →	+0.087	+0.391	<.001	.009	3	10
OESOPHAGUS	Positive regulation of chromosome condensation →	+0.212	+0.715	.001	.004	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,256 associations by consensus.

Dihydrofolate metabolic process by MOCS2 expression — OESOPHAGUS

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