MOCS1

Across TCGA cell cohorts, MOCS1 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,462 significant associations in total. BONE shows the largest number of these associations.

The most reproducible MOCS1-associated GO terms across cancer lineages are Positive regulation of transcription initiation by RNA polymerase II, Transcription initiation at RNA polymerase II promoter, and RNA polymerase II preinitiation complex assembly. Each is linked with MOCS1 in more than 11 cancer types. Because this analysis shows association rather than direction, both MOCS1-to-partner and partner-to-MOCS1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of transcription initiation by RNA polymerase II grouped by MOCS1-low versus MOCS1-high in KIDNEY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MOCS1→partner) and Y-score (partner→MOCS1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
KIDNEY	Positive regulation of transcription initiation by RNA polymerase II →	+0.082	+1.253	.001	.008	3	12
SOFT_TISSUE	Transcription initiation at RNA polymerase II promoter →	+0.072	+1.436	<.001	<.001	3	12
BLOOD_Leukemia	RNA polymerase II preinitiation complex assembly →	+0.053	+1.131	<.001	.002	3	11
SOFT_TISSUE	DNA-templated transcription initiation →	+0.065	+1.125	<.001	<.001	3	11
SOFT_TISSUE	Positive regulation of DNA-templated transcription initiation →	+0.075	+1.273	<.001	<.001	3	11
SOFT_TISSUE	Positive regulation of DNA-templated transcription, elongation →	+0.071	+1.094	<.001	.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,462 associations by consensus.

Positive regulation of transcription initiation by RNA polymerase II by MOCS1 expression — KIDNEY

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