MOCS1

Across TCGA cell cohorts, MOCS1 mutation is significantly associated with the RNA expression of many other genes, with 21 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible MOCS1-associated genes across cancer lineages are OR10A5, OXGR1, and GSG1L2. Each is linked with MOCS1 in more than 1 cancer types. Because this analysis shows association rather than direction, both MOCS1-to-partner and partner-to-MOCS1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR10A5 grouped by MOCS1-low versus MOCS1-high in OESOPHAGUS.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MOCS1→partner) and Y-score (partner→MOCS1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	OR10A5 →	+0.030	+4.906	<.001	.006	3	1
BLOOD_Leukemia	OXGR1 →	+0.123	+3.847	<.001	.007	3	1
BLOOD_Leukemia	GSG1L2 →	+0.034	+4.384	<.001	.006	3	1
LUNG_SCLC	OR10G3 →	+0.063	+5.643	<.001	.002	3	1
LUNG_SCLC	SPATA31D1 →	+0.843	+5.643	<.001	.002	3	1
LUNG_SCLC	TEX50 →	+0.040	+5.643	<.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 21 associations by consensus.

OR10A5 by MOCS1 expression — OESOPHAGUS

Explore this box plot interactively →