MOB4

Across TCGA cell cohorts, MOB4 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,797 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible MOB4-associated GO terms across cancer lineages are Regulation of DNA damage checkpoint, Immunoglobulin V(D)J recombination, and Negative regulation of mitotic sister chromatid separation. Each is linked with MOB4 in more than 12 cancer types. Because this analysis shows association rather than direction, both MOB4-to-partner and partner-to-MOB4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of DNA damage checkpoint grouped by MOB4-low versus MOB4-high in KIDNEY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MOB4→partner) and Y-score (partner→MOB4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
KIDNEY	Regulation of DNA damage checkpoint →	+0.074	+0.464	<.001	<.001	3	13
SOFT_TISSUE	Immunoglobulin V(D)J recombination →	+0.148	+0.635	<.001	<.001	3	12
KIDNEY	Negative regulation of mitotic sister chromatid separation →	+0.116	+0.508	.007	.001	3	11
KIDNEY	Negative regulation of sister chromatid segregation →	+0.116	+0.508	.007	.001	3	11
KIDNEY	Negative regulation of mitotic sister chromatid segregation →	+0.116	+0.508	.007	.001	3	11
KIDNEY	Negative regulation of mitotic metaphase/anaphase transition →	+0.116	+0.508	.007	.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,797 associations by consensus.

Regulation of DNA damage checkpoint by MOB4 expression — KIDNEY

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