MOB3C

Across TCGA cell cohorts, MOB3C mutation is significantly associated with the RNA expression of many other genes, with 2 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible MOB3C-associated genes across cancer lineages are OR5P3 and AADACL4. Each is linked with MOB3C in more than 1 cancer types. Because this analysis shows association rather than direction, both MOB3C-to-partner and partner-to-MOB3C results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR5P3 grouped by MOB3C-low versus MOB3C-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MOB3C→partner) and Y-score (partner→MOB3C) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	OR5P3 →	+0.108	+5.201	<.001	.006	3	1
BLOOD_Leukemia	AADACL4 →	+0.026	+4.922	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

OR5P3 by MOB3C expression — BLOOD_Leukemia

Explore this box plot interactively →