MOB2

Across TCGA cell cohorts, MOB2 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,140 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible MOB2-associated GO terms across cancer lineages are Telomere tethering at nuclear periphery, Methylglyoxal metabolic process, and Cellular response to methylglyoxal. Each is linked with MOB2 in more than 12 cancer types. Because this analysis shows association rather than direction, both MOB2-to-partner and partner-to-MOB2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Telomere tethering at nuclear periphery grouped by MOB2-low versus MOB2-high in URINARY_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MOB2→partner) and Y-score (partner→MOB2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
URINARY_TRACT	Telomere tethering at nuclear periphery →	+0.141	+0.725	.001	.001	3	13
OESOPHAGUS	Methylglyoxal metabolic process →	+0.190	+0.896	<.001	.002	2	13
OESOPHAGUS	Cellular response to methylglyoxal →	+0.236	+1.092	<.001	<.001	3	12
SOFT_TISSUE	Response to mitochondrial depolarisation →	+0.132	+0.758	<.001	<.001	3	12
OESOPHAGUS	Methylglyoxal catabolic process →	+0.241	+0.897	<.001	.002	3	12
OESOPHAGUS	Cellular detoxification of methylglyoxal →	+0.236	+1.092	<.001	<.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,140 associations by consensus.

Telomere tethering at nuclear periphery by MOB2 expression — URINARY_TRACT

Explore this box plot interactively →