MNX1

Across TCGA patient cohorts, MNX1 mutation is significantly associated with the RNA expression of many other genes, with 1,438 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible MNX1-associated genes across cancer lineages are RNU6-33P, RNU6ATAC30P, and RPS3AP9. Each is linked with MNX1 in more than 1 cancer types. Because this analysis shows association rather than direction, both MNX1-to-partner and partner-to-MNX1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6-33P grouped by MNX1-low versus MNX1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MNX1→partner) and Y-score (partner→MNX1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RNU6-33P →	+0.499	+2.310	.002	.002	3	2
UCEC	RNU6ATAC30P →	+0.326	+2.002	.001	.006	3	2
UCEC	RPS3AP9 →	+0.096	+2.146	<.001	.006	3	2
COAD	RNU7-119P →	+0.791	+4.721	<.001	.004	3	2
SKCM	MIR301A →	+0.441	+5.159	<.001	.007	3	1
SKCM	RPL23AP45 →	+0.101	+5.097	<.001	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,438 associations by consensus.

RNU6-33P by MNX1 expression — UCEC

Explore this box plot interactively →