MNS1

Across TCGA patient cohorts, MNS1 mutation is significantly associated with the RNA expression of many other genes, with 3,131 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible MNS1-associated genes across cancer lineages are BPNT2P, ECEL1P1, and LINC01072. Each is linked with MNS1 in more than 1 cancer types. Because this analysis shows association rather than direction, both MNS1-to-partner and partner-to-MNS1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, BPNT2P grouped by MNS1-low versus MNS1-high in READ.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MNS1→partner) and Y-score (partner→MNS1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
READ	BPNT2P →	+0.148	+6.681	<.001	<.001	3	2
BRCA	ECEL1P1 →	+0.127	+4.232	<.001	.009	3	2
UCEC	LINC01072 →	+0.108	+1.986	.001	.007	3	2
UCEC	RNA5SP413 →	+0.906	+1.639	<.001	.008	3	2
UCEC	RNU6-965P →	+0.171	+3.668	<.001	.009	3	2
UCEC	RNA5SP422 →	+0.744	+2.033	<.001	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,131 associations by consensus.

BPNT2P by MNS1 expression — READ

Explore this box plot interactively →