MMUT

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, MMUT protein abundance is significantly associated with the RNA expression of many other genes, with 10,155 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible MMUT-associated genes across cancer lineages are TGFB1, ARSI, and KIFC3. Each is linked with MMUT in more than 7 cancer types. Because this analysis shows association rather than direction, both MMUT-to-partner and partner-to-MMUT results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, MMUT versus TGFB1 in BRCA, with a Pearson correlation of -0.38.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MMUT→partner) and Y-score (partner→MMUT) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BRCATGFB1 →-0.871-0.372<.001<.00137
HNSCARSI →-0.888-0.214.009.00718
BRCAKIFC3 →-0.856-0.380<.001<.00136
PDACSPOCD1 →-0.930-0.356<.001<.00136
OVAEBP1 →-1.800-0.303<.001.00135
BRCAGFPT2 →-0.921-0.367<.001<.00135
Each partner links to its Q-omics profile. Showing the 6 strongest of 10,155 associations by consensus.

MMUT vs TGFB1 — BRCA

Per-sample scatter of MMUT vs TGFB1 in BRCA (Pearson r = -0.38).

Explore this scatter interactively →

Exploration