MMUT

Across TCGA pan-cancer cohorts, MMUT RNA is linked to patient survival in 23 of 34 cancer types, making it the most broadly survival-associated MMUT data layer compared with 5 for mutation status and 5 for mass-spec protein.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher MMUT RNA is associated with better overall survival. In most high-consensus cancer types, elevated MMUT expression acts as an unfavorable survival marker, although some lineages such as KIRC and LUAD show a favorable association.

KIRC, LUAD, and UCS are the cancer types where MMUT RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRC	OS	Median	All	0.752	0.515	<.001	144	view →
LUAD	DFS	Median	All	0.819	0.710	.006	42	view →
UCS	DFS	Tertile	IV	0.996	0.321	.024	36	view →
UVM	OS	Median	III,IV	0.296	1.000	.005	31	view →
CHOL	DFS	Median	III,IV	0.127	0.647	.006	26	view →
KIRP	OS	Median	All	0.823	0.585	.003	23	view →
READ	OS	Median	II,III,IV	0.963	0.449	.007	18	view →
ESCA	OS	Tertile	IV	0.238	0.738	.024	18	view →
SARC	OS	Tertile	All	0.499	0.840	.002	17	view →
PRAD	DFS	Tertile	All	0.937	0.861	.014	14	view →
SKCM	DFS	Quartile	All	0.703	0.526	.002	13	view →
ACC	DFS	Tertile	III,IV	0.553	0.074	.001	11	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 23 lineages.

MMUT–KIRC (OS)

Open the KIRC breakdown →