MMUT

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, MMUT protein abundance is significantly associated with the protein abundance of many other proteins, with 15,366 significant associations in total. GBM shows the largest number of these associations.

The most reproducible MMUT-associated proteins across cancer lineages are IARS2, MCCC1, and MCCC2. Each is linked with MMUT in more than 9 cancer types. Because this analysis shows association rather than direction, both MMUT-to-partner and partner-to-MMUT results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, MMUT versus IARS2 in OV, with a Pearson correlation of 0.44.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (MMUT→partner) and Y-score (partner→MMUT) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
OVIARS2 →+0.561+0.356<.001<.001310
LSCCMCCC1 →+0.532+0.385<.001<.001310
BRCAMCCC2 →+0.702+0.381<.001<.001310
OVMMAA →+0.499+0.326<.001<.001310
COADSUCLG1 →+0.437+0.353<.001<.001310
OVSUCLG2 →+0.634+0.353<.001<.001310
Each partner links to its Q-omics profile. Showing the 6 strongest of 15,366 associations by consensus.

MMUT vs IARS2 — OV

Per-sample scatter of MMUT vs IARS2 in OV (Pearson r = 0.44).

Explore this scatter interactively →

Exploration