MMRN2

Across TCGA cell cohorts, MMRN2 mutation is significantly associated with the RNA expression of many other genes, with 136 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible MMRN2-associated genes across cancer lineages are ACER1, OR1Q1, and TEKT1. Each is linked with MMRN2 in more than 1 cancer types. Because this analysis shows association rather than direction, both MMRN2-to-partner and partner-to-MMRN2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ACER1 grouped by MMRN2-low versus MMRN2-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MMRN2→partner) and Y-score (partner→MMRN2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	ACER1 →	+0.075	+2.086	<.001	.009	3	2
BLOOD_Leukemia	OR1Q1 →	+0.367	+3.714	<.001	.005	3	1
BLOOD_Leukemia	TEKT1 →	+0.272	+3.959	<.001	.005	3	1
BLOOD_Leukemia	OR13J1 →	+0.164	+4.096	<.001	.001	3	1
BLOOD_Leukemia	TMEM196 →	+0.029	+3.289	<.001	.009	3	1
BLOOD_Leukemia	NKX2-6 →	+0.325	+4.201	<.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 136 associations by consensus.

ACER1 by MMRN2 expression — LARGE_INTESTINE

Explore this box plot interactively →