MMP9

Across TCGA patient cohorts, MMP9 RNA expression is significantly associated with the protein abundance of many other proteins, with 10,766 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible MMP9-associated proteins across cancer lineages are FN1, MXRA5, and CTHRC1. Each is linked with MMP9 in more than 7 cancer types. Because this analysis shows association rather than direction, both MMP9-to-partner and partner-to-MMP9 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, MMP9 versus FN1 in OV, with a Pearson correlation of 0.45.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (MMP9→partner) and Y-score (partner→MMP9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	FN1 →	+1.175	+2.100	<.001	<.001	3	8
CCRCC	MXRA5 →	+1.210	+2.009	<.001	<.001	3	8
COAD	CTHRC1 →	+1.168	+1.556	<.001	<.001	3	7
GBM	HK3 →	+0.855	+1.724	.001	.002	3	7
OV	PLAU →	+0.685	+1.206	<.001	.001	3	7
GBM	PLOD1 →	+0.565	+1.965	<.001	.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,766 associations by consensus.

MMP9 vs FN1 — OV

Explore this scatter interactively →