MMP26

Across TCGA pan-cancer cohorts, MMP26 Mutation is linked to patient survival in 6 of 34 cancer types, making it a survival-associated MMP26 data layer compared with 18 for mass-spec protein.

The strongest signal is observed in breast invasive carcinoma (BRCA), where higher MMP26 Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated MMP26 expression acts as an unfavorable survival marker.

BRCA, SKCM, and COAD are the cancer types where MMP26 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
BRCA	OS	Median	All	0.106	0.579	<.001	28	view →
SKCM	DFS	Median	IV	0.036	0.433	<.001	12	view →
COAD	DFS	Median	All	0.510	0.790	.012	6	view →
LIHC	OS	Median	III,IV	0.195	0.648	.013	6	view →
LUAD	OS	Median	III,IV	0.171	0.669	.001	6	view →
UCEC	OS	Median	IV	0.231	0.592	.036	6	view →

Pink = unfavorable, green = favorable. Showing the 6 strongest of 6 lineages.

MMP26–BRCA (OS)

Open the BRCA breakdown →