MMP25-AS1

Across TCGA patient cohorts, MMP25-AS1 RNA expression is significantly associated with the go_rna of many other GO terms, with 7,159 significant associations in total. KIRC shows the largest number of these associations.

The most reproducible MMP25-AS1-associated GO terms across cancer lineages are Protein localization to vacuole, Positive regulation of establishment of protein localization to mitochondrion, and Regulation of binding. Each is linked with MMP25-AS1 in more than 29 cancer types. Because this analysis shows association rather than direction, both MMP25-AS1-to-partner and partner-to-MMP25-AS1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Protein localization to vacuole grouped by MMP25-AS1-low versus MMP25-AS1-high in KIRC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MMP25-AS1→partner) and Y-score (partner→MMP25-AS1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
KIRC	Protein localization to vacuole →	+0.047	+1.042	<.001	<.001	3	30
KIRC	Positive regulation of establishment of protein localization to mitochondrion →	+0.060	+1.132	<.001	<.001	3	30
STAD	Regulation of binding →	+0.044	+0.581	<.001	<.001	3	30
KIRC	Internal protein amino acid acetylation →	+0.057	+1.019	<.001	<.001	3	30
KIRC	Obsolete histone modification →	+0.055	+1.152	<.001	<.001	3	30
KIRC	TOR signaling →	+0.042	+1.043	<.001	<.001	3	30

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,159 associations by consensus.

Protein localization to vacuole by MMP25-AS1 expression — KIRC

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