MMP16

Across TCGA cell cohorts, MMP16 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,995 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible MMP16-associated GO terms across cancer lineages are Cerebral cortex tangential migration, Protein localization to site of double-strand break, and Negative regulation of negative chemotaxis. Each is linked with MMP16 in more than 10 cancer types. Because this analysis shows association rather than direction, both MMP16-to-partner and partner-to-MMP16 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Cerebral cortex tangential migration grouped by MMP16-low versus MMP16-high in BLOOD_Myeloma.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MMP16→partner) and Y-score (partner→MMP16) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Myeloma	Cerebral cortex tangential migration →	+1.639	+2.197	<.001	.001	3	11
OESOPHAGUS	Protein localization to site of double-strand break →	+0.083	+0.599	.003	.004	2	10
BLOOD_Myeloma	Negative regulation of negative chemotaxis →	+1.469	+2.143	<.001	.002	3	8
OVARY	Regulation of blood-brain barrier permeability →	-0.288	-0.848	<.001	<.001	3	8
BONE	Regulation of intracellular transport →	+0.063	+1.608	.005	<.001	3	8
STOMACH	Positive regulation of chromosome organization →	+0.076	+1.561	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,995 associations by consensus.

Cerebral cortex tangential migration by MMP16 expression — BLOOD_Myeloma

Explore this box plot interactively →