MMP11

Across TCGA cell cohorts, MMP11 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,507 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible MMP11-associated GO terms across cancer lineages are Regulation of myoblast fusion, ERAD pathway, and Regulation of syncytium formation by plasma membrane fusion. Each is linked with MMP11 in more than 10 cancer types. Because this analysis shows association rather than direction, both MMP11-to-partner and partner-to-MMP11 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of myoblast fusion grouped by MMP11-low versus MMP11-high in STOMACH.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MMP11→partner) and Y-score (partner→MMP11) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	Regulation of myoblast fusion →	+0.085	+1.118	<.001	<.001	3	11
OESOPHAGUS	ERAD pathway →	+0.111	+2.054	.003	<.001	3	10
STOMACH	Regulation of syncytium formation by plasma membrane fusion →	+0.117	+1.699	<.001	<.001	3	10
OESOPHAGUS	ATP synthesis coupled electron transport →	+0.109	+1.223	<.001	.003	3	10
OESOPHAGUS	Mitochondrial ATP synthesis coupled electron transport →	+0.109	+1.223	<.001	.003	3	10
OESOPHAGUS	Oxidative phosphorylation →	+0.103	+1.288	<.001	.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,507 associations by consensus.

Regulation of myoblast fusion by MMP11 expression — STOMACH

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