MMP10

Across TCGA pan-cancer cohorts, MMP10 mass-spec protein is linked to patient survival in 3 of 34 cancer types, making it a survival-associated MMP10 data layer compared with 21 for mass-spec protein and 5 for mutation status.

The strongest signal is observed in lung adenocarcinoma (LUAD), where higher MMP10 mass-spec protein is associated with worse disease-free survival. In most high-consensus cancer types, elevated MMP10 expression acts as an unfavorable survival marker.

LUAD, PDAC, and HNSC are the cancer types where MMP10 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUAD	DFS	Median	All	0.447	0.941	<.001	17	view →
PDAC	DFS	Median	IV	0.217	0.749	.024	14	view →
HNSC	DFS	Median	IV	0.328	0.889	.014	2	view →

Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

MMP10–LUAD (DFS)

Open the LUAD breakdown →