MMP10

Across TCGA cell cohorts, MMP10 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,640 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible MMP10-associated GO terms across cancer lineages are Regulation of protein import into nucleus, Regulation of positive chemotaxis, and Positive regulation of positive chemotaxis. Each is linked with MMP10 in more than 5 cancer types. Because this analysis shows association rather than direction, both MMP10-to-partner and partner-to-MMP10 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of protein import into nucleus grouped by MMP10-low versus MMP10-high in SOFT_TISSUE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MMP10→partner) and Y-score (partner→MMP10) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	Regulation of protein import into nucleus →	+0.076	+2.586	<.001	<.001	3	6
URINARY_TRACT	Regulation of positive chemotaxis →	+0.226	+2.284	<.001	.001	3	5
URINARY_TRACT	Positive regulation of positive chemotaxis →	+0.226	+2.284	<.001	.001	3	5
BLOOD_Myeloma	Cellular response to nutrient levels →	+0.037	+0.056	.002	.001	3	5
BLOOD_Myeloma	Pyrimidine nucleobase metabolic process →	-0.084	-0.037	.006	.006	3	5
UPPER_AERODIGESTIVE_TRACT	Labyrinthine layer development →	+0.163	+3.898	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,640 associations by consensus.

Regulation of protein import into nucleus by MMP10 expression — SOFT_TISSUE

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