MMGT1

Across TCGA patient cohorts, MMGT1 mutation is significantly associated with the RNA expression of many other genes, with 1,842 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible MMGT1-associated genes across cancer lineages are RNU1-17P, RNU1-62P, and LINC00459. Each is linked with MMGT1 in more than 2 cancer types. Because this analysis shows association rather than direction, both MMGT1-to-partner and partner-to-MMGT1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU1-17P grouped by MMGT1-low versus MMGT1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MMGT1→partner) and Y-score (partner→MMGT1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RNU1-17P →	+0.149	+1.997	.001	.005	3	3
CESC	RNU1-62P →	+0.304	+6.124	<.001	<.001	3	2
CESC	LINC00459 →	+0.075	+4.669	<.001	.007	3	2
LUAD	RNU6-1040P →	+0.497	+7.930	<.001	.008	3	2
COAD	RNU6-1175P →	+0.977	+5.693	<.001	.003	3	2
COAD	RNU2-34P →	+0.857	+6.721	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,842 associations by consensus.

RNU1-17P by MMGT1 expression — UCEC

Explore this box plot interactively →