MMGT1

Across TCGA cell cohorts, MMGT1 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,682 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible MMGT1-associated GO terms across cancer lineages are Cytosolic ciliogenesis, Protein insertion into ER membrane by stop-transfer membrane-anchor sequence, and Tail-anchored membrane protein insertion into ER membrane. Each is linked with MMGT1 in more than 15 cancer types. Because this analysis shows association rather than direction, both MMGT1-to-partner and partner-to-MMGT1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Cytosolic ciliogenesis grouped by MMGT1-low versus MMGT1-high in BREAST.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MMGT1→partner) and Y-score (partner→MMGT1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	Cytosolic ciliogenesis →	+0.160	+1.140	<.001	<.001	3	16
BREAST	Protein insertion into ER membrane by stop-transfer membrane-anchor sequence →	+0.159	+1.168	<.001	<.001	3	14
UPPER_AERODIGESTIVE_TRACT	Tail-anchored membrane protein insertion into ER membrane →	+0.111	+0.839	<.001	<.001	3	13
BLOOD_Lymphoma	Cellular response to environmental stimulus →	+0.035	+0.779	<.001	<.001	3	12
BLOOD_Lymphoma	Cellular response to abiotic stimulus →	+0.035	+0.779	<.001	<.001	3	12
PANCREAS	Cobalt ion transport →	+0.128	+0.810	<.001	<.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,682 associations by consensus.

Cytosolic ciliogenesis by MMGT1 expression — BREAST

Explore this box plot interactively →