MMEL1-AS1

Across TCGA pan-cancer cohorts, MMEL1-AS1 RNA is linked to patient survival in 14 of 34 cancer types, making it the most broadly survival-associated MMEL1-AS1 data layer.

The strongest signal is observed in adrenocortical carcinoma (ACC), where higher MMEL1-AS1 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated MMEL1-AS1 expression acts as an unfavorable survival marker, although some lineages such as READ and LUSC show a favorable association.

ACC, READ, and KIRC are the cancer types where MMEL1-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
ACC	DFS	Tertile	All	0.178	0.655	<.001	48	view →
READ	DFS	Median	All	0.915	0.754	.007	48	view →
KIRC	DFS	Tertile	III,IV	0.247	0.759	<.001	36	view →
THCA	OS	Tertile	All	0.769	0.957	<.001	33	view →
PCPG	DFS	Tertile	All	0.368	0.796	<.001	21	view →
SARC	OS	Tertile	All	0.162	0.526	.011	21	view →
SKCM	DFS	Tertile	IV	0.036	0.433	<.001	18	view →
UCS	DFS	Median	IV	0.440	0.885	.015	18	view →
BLCA	OS	Tertile	IV	0.141	0.573	.034	9	view →
ESCA	OS	Tertile	All	0.455	0.717	.009	9	view →
LUSC	OS	Tertile	All	0.865	0.665	.027	9	view →
HNSC	DFS	Tertile	IV	0.838	0.308	.032	9	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 14 lineages.

MMEL1-AS1–ACC (DFS)

Open the ACC breakdown →