MMEL1-AS1

Across TCGA pan-cancer cohorts, MMEL1-AS1 RNA differs between tumor and matched normal tissue in 5 of 18 cancer types tested, making tumor–normal expression one of MMEL1-AS1’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where MMEL1-AS1 RNA is repressed in tumor relative to normal tissue. In most cancer types MMEL1-AS1 is over-expressed in tumor, although a few such as KIRC and KIRP show the opposite, repressed pattern.

KIRC, KIRP, and COAD are the cancer types where MMEL1-AS1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in MMEL1-AS1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRC	Female	All	−0.834	<.001	11	view →
KIRP	Male	All	−0.941	<.001	6	view →
COAD	All	All	+0.201	.033	3	view →
BRCA	All	All	−0.023	.027	2	view →
KICH	All	III,IV	+2.622	.037	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 5 strongest of 5 lineages.

MMEL1-AS1–KIRC

Open the KIRC breakdown →