MMADHC-DT

Across TCGA pan-cancer cohorts, MMADHC-DT RNA is linked to patient survival in 22 of 34 cancer types, making it the most broadly survival-associated MMADHC-DT data layer.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher MMADHC-DT RNA is associated with better overall survival. In most high-consensus cancer types, elevated MMADHC-DT expression acts as an unfavorable survival marker, although some lineages such as KIRC and KIRP show a favorable association.

KIRC, KIRP, and STAD are the cancer types where MMADHC-DT RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRC	OS	Tertile	All	0.774	0.551	<.001	146	view →
KIRP	DFS	Median	II,III,IV	0.894	0.255	.005	30	view →
STAD	DFS	Tertile	II,III,IV	0.515	0.801	.004	24	view →
BRCA	DFS	Tertile	All	0.928	0.880	.009	19	view →
UCS	OS	Median	IV	0.248	0.673	.033	18	view →
LIHC	OS	Median	III,IV	0.522	0.199	.013	18	view →
OV	OS	Tertile	IV	0.538	0.308	.016	14	view →
GBM	DFS	Quartile	All	0.413	0.154	.005	11	view →
ESCA	DFS	Tertile	III,IV	0.284	0.518	.018	9	view →
MESO	DFS	Tertile	III,IV	0.634	0.130	.026	6	view →
KICH	DFS	Median	All	0.724	0.939	.016	5	view →
SARC	OS	Quartile	All	0.861	0.744	.037	4	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 22 lineages.

MMADHC-DT–KIRC (OS)

Open the KIRC breakdown →