MLYCD

Across TCGA patient cohorts, MLYCD mutation is significantly associated with the RNA expression of many other genes, with 1,739 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible MLYCD-associated genes across cancer lineages are RNU6-545P, SNORD114-2, and RNU6-378P. Each is linked with MLYCD in more than 1 cancer types. Because this analysis shows association rather than direction, both MLYCD-to-partner and partner-to-MLYCD results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6-545P grouped by MLYCD-low versus MLYCD-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MLYCD→partner) and Y-score (partner→MLYCD) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	RNU6-545P →	+1.538	+5.392	<.001	.002	3	2
COAD	SNORD114-2 →	+0.851	+5.917	<.001	.001	3	2
COAD	RNU6-378P →	+0.968	+5.173	<.001	.001	3	2
COAD	RNU1-148P →	+1.029	+5.547	<.001	.002	3	2
COAD	RNU6-306P →	+1.339	+6.101	<.001	<.001	3	2
COAD	RNU1-3 →	+1.648	+5.122	<.001	.004	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,739 associations by consensus.

RNU6-545P by MLYCD expression — COAD

Explore this box plot interactively →