Q-omics provides the consensus-scored RNU1-3 profile across patient tissues and cancer cell-line models. RNU1-3 expression is associated with patient survival in 5 of 34 cancer types, with the highest sampling consensus in UCEC. Additionally, RNU1-3 RNA expression shows 4,569 significant gene co-expression associations, with the highest sampling consensus in LUAD. Together, these results highlight UCEC, and LUAD as cancer lineages where RNU1-3 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.

Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.

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Survival associations

This table summarizes RNU1-3 survival associations across molecular data types. RNU1-3 RNA expression shows survival associations in the most cancer types (5). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.

RNU1-3 data type	Survival analysis	Lineage consensus	Lineage of highest sampling consensus
RNA	Kaplan–Meier	5	UCEC (72)	view →

This table ranks reproducible RNU1-3 RNA expression–survival associations across cancer types. High RNU1-3 expression shows unfavorable associations in UCEC, BRCA, SKCM, THCA and BLCA. The UCEC Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p < 0.001). Together, the overview and detailed table identify UCEC as the clearest survival context for RNU1-3 RNA expression.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCEC	DFS	Tertile	All	0.340	0.653	<.001	72	view →
BRCA	DFS	Tertile	All	0.365	0.529	.003	48	view →
SKCM	OS	Tertile	III,IV	0.216	0.721	.001	36	view →
THCA	OS	Tertile	All	0.323	0.955	.007	24	view →
BLCA	OS	Tertile	All	0.204	0.687	.028	18	view →

Pink = unfavorable, green = favorable. all 5 lineages →

RNU1-3-UCEC (DFS)

Kaplan–Meier survival curve for RNU1-3 RNA expression in UCEC: high vs low expression groups.

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Cross-omics associations

This table shows molecular features associated with RNU1-3 in patient tissues and cancer cell lines. In patient samples, RNU1-3 shows the broadest associations at the RNA and protein expression levels, with LUAD recurring as the lineage with the largest associated feature set.

Associated data type	Strength (# associated data)	Lineage of highest associated data
▼RNA
RNA	4,569	LUAD (2961)	view →
Protein (mass-spec)	2,504	CCRCC (590)	view →