MLYCD

Across TCGA cell cohorts, MLYCD mutation is significantly associated with the RNA expression of many other genes, with 15 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible MLYCD-associated genes across cancer lineages are OR14K1, PPEF2, and C1QTNF7. Each is linked with MLYCD in more than 1 cancer types. Because this analysis shows association rather than direction, both MLYCD-to-partner and partner-to-MLYCD results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR14K1 grouped by MLYCD-low versus MLYCD-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MLYCD→partner) and Y-score (partner→MLYCD) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	OR14K1 →	+0.068	+4.022	<.001	.006	3	1
LARGE_INTESTINE	PPEF2 →	+0.043	+3.736	<.001	.007	3	1
LARGE_INTESTINE	C1QTNF7 →	+0.105	+4.523	<.001	.001	3	1
LARGE_INTESTINE	VN1R3 →	+0.010	+4.022	<.001	.006	3	1
LARGE_INTESTINE	CYLC1 →	+0.003	+4.022	<.001	.006	3	1
LARGE_INTESTINE	FCAR →	+0.024	+3.345	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 15 associations by consensus.

OR14K1 by MLYCD expression — LARGE_INTESTINE

Explore this box plot interactively →