MLXIPL

Across TCGA patient cohorts, MLXIPL protein abundance is significantly associated with the RNA expression of many other genes, with 272 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible MLXIPL-associated genes across cancer lineages are PCK2, PGK1, and DYRK4. Each is linked with MLXIPL in more than 1 cancer types. Because this analysis shows association rather than direction, both MLXIPL-to-partner and partner-to-MLXIPL results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, MLXIPL versus PCK2 in CCRCC, with a Pearson correlation of 0.30.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MLXIPL→partner) and Y-score (partner→MLXIPL) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CCRCC	PCK2 →	+0.464	+0.336	<.001	.001	3	1
CCRCC	PGK1 →	+0.373	+0.290	.003	.007	3	1
CCRCC	DYRK4 →	-0.213	-0.413	.006	.003	3	1
CCRCC	PEX11G →	+0.321	+0.345	.006	.001	3	1
CCRCC	HOXA2 →	-0.307	-0.369	.008	<.001	3	1
CCRCC	MOGAT3 →	+1.468	+0.515	.002	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 272 associations by consensus.

MLXIPL vs PCK2 — CCRCC

Explore this scatter interactively →