MLXIPL

Across TCGA cell cohorts, MLXIPL RNA expression is significantly associated with the go_rna of many other GO terms, with 4,540 significant associations in total. BONE shows the largest number of these associations.

The most reproducible MLXIPL-associated GO terms across cancer lineages are Regulation of myoblast fusion, Hexose mediated signaling, and Sugar mediated signaling pathway. Each is linked with MLXIPL in more than 13 cancer types. Because this analysis shows association rather than direction, both MLXIPL-to-partner and partner-to-MLXIPL results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of myoblast fusion grouped by MLXIPL-low versus MLXIPL-high in SKIN.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MLXIPL→partner) and Y-score (partner→MLXIPL) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	Regulation of myoblast fusion →	+0.097	+0.480	<.001	<.001	2	14
LUNG_NSCLC_LUSC	Hexose mediated signaling →	-0.263	-1.461	.001	<.001	2	12
LUNG_NSCLC_LUSC	Sugar mediated signaling pathway →	-0.263	-1.461	.001	<.001	2	12
LUNG_NSCLC_LUSC	Glucose mediated signaling pathway →	-0.263	-1.461	.001	<.001	2	12
OVARY	Copper ion export →	-0.174	-1.669	<.001	<.001	3	11
LIVER	Fatty acid beta-oxidation →	+0.130	+4.079	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,540 associations by consensus.

Regulation of myoblast fusion by MLXIPL expression — SKIN

Explore this box plot interactively →