MLLT1

Across TCGA pan-cancer cohorts, MLLT1 mass-spec protein is linked to patient survival in 5 of 34 cancer types, making it a survival-associated MLLT1 data layer compared with 26 for mass-spec protein and 8 for mutation status.

The strongest signal is observed in lung adenocarcinoma (LUAD), where higher MLLT1 mass-spec protein is associated with better overall survival. In most high-consensus cancer types, elevated MLLT1 expression acts as an unfavorable survival marker, although some lineages such as LUAD and PDAC show a favorable association.

LUAD, PDAC, and HNSC are the cancer types where MLLT1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUAD	OS	Median	III,IV	1.000	0.770	.006	29	view →
PDAC	DFS	Tertile	IV	0.934	0.235	.024	15	view →
HNSC	DFS	Quartile	II,III,IV	0.905	1.000	.015	8	view →
UCEC	DFS	Tertile	All	0.836	0.943	.040	6	view →
GBM	DFS	Median	All	0.200	0.328	.024	5	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

MLLT1–LUAD (OS)

Open the LUAD breakdown →