MLLT1

Across TCGA patient cohorts, MLLT1 protein abundance is significantly associated with the RNA expression of many other genes, with 14,662 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible MLLT1-associated genes across cancer lineages are NOD2, METTL4, and HAMP. Each is linked with MLLT1 in more than 4 cancer types. Because this analysis shows association rather than direction, both MLLT1-to-partner and partner-to-MLLT1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, MLLT1 versus NOD2 in GBM, with a Pearson correlation of -0.35.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MLLT1→partner) and Y-score (partner→MLLT1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	NOD2 →	-0.715	-0.198	<.001	.001	3	5
LSCC	METTL4 →	+0.532	+0.217	<.001	<.001	3	4
GBM	HAMP →	-0.947	-0.233	<.001	<.001	3	4
GBM	LY86 →	-0.651	-0.246	<.001	<.001	3	4
HNSC	PRPF3 →	+0.479	+0.156	.001	.002	3	4
LSCC	PARP2 →	+0.626	+0.304	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,662 associations by consensus.

MLLT1 vs NOD2 — GBM

Explore this scatter interactively →