MLLT1

Across TCGA cell cohorts, MLLT1 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,467 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible MLLT1-associated GO terms across cancer lineages are Regulation of protein localization to chromatin, Positive regulation of anaphase-promoting complex-dependent catabolic process, and Subtelomeric heterochromatin formation. Each is linked with MLLT1 in more than 16 cancer types. Because this analysis shows association rather than direction, both MLLT1-to-partner and partner-to-MLLT1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of protein localization to chromatin grouped by MLLT1-low versus MLLT1-high in SOFT_TISSUE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MLLT1→partner) and Y-score (partner→MLLT1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	Regulation of protein localization to chromatin →	+0.115	+1.103	<.001	<.001	3	17
BONE	Positive regulation of anaphase-promoting complex-dependent catabolic process →	+0.140	+0.748	<.001	<.001	3	16
BONE	Subtelomeric heterochromatin formation →	+0.133	+1.023	<.001	<.001	3	16
STOMACH	Epigenetic regulation of gene expression →	+0.080	+0.831	<.001	.007	3	16
UPPER_AERODIGESTIVE_TRACT	DNA-templated transcription initiation →	+0.081	+0.977	.001	<.001	3	16
URINARY_TRACT	Positive regulation of gene expression, epigenetic →	+0.075	+1.091	.001	<.001	3	16

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,467 associations by consensus.

Regulation of protein localization to chromatin by MLLT1 expression — SOFT_TISSUE

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