MLIP-AS1

Across TCGA pan-cancer cohorts, MLIP-AS1 RNA is linked to patient survival in 17 of 34 cancer types, making it the most broadly survival-associated MLIP-AS1 data layer.

The strongest signal is observed in thyroid carcinoma (THCA), where higher MLIP-AS1 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated MLIP-AS1 expression acts as an unfavorable survival marker, although some lineages such as UCS and ACC show a favorable association.

THCA, UCEC, and CHOL are the cancer types where MLIP-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
THCA	OS	Median	All	0.755	1.000	<.001	60	view →
UCEC	DFS	Tertile	All	0.833	0.911	.002	42	view →
CHOL	DFS	Tertile	All	0.133	0.496	.033	36	view →
KIRC	DFS	Median	All	0.559	0.676	<.001	34	view →
UCS	DFS	Quartile	All	0.693	0.218	.023	18	view →
PAAD	DFS	Tertile	III,IV	0.118	0.734	.014	18	view →
READ	OS	Tertile	All	0.793	0.929	.004	15	view →
STAD	DFS	Tertile	IV	0.083	0.379	.001	12	view →
HNSC	OS	Median	IV	0.371	0.615	.005	8	view →
KICH	OS	Median	All	0.927	1.000	.018	7	view →
ACC	OS	Median	II,III,IV	0.874	0.685	.023	7	view →
BRCA	DFS	Tertile	IV	1.000	0.638	.042	6	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 17 lineages.

MLIP-AS1–THCA (OS)

Open the THCA breakdown →