MLIP-AS1

Across TCGA pan-cancer cohorts, MLIP-AS1 RNA differs between tumor and matched normal tissue in 8 of 18 cancer types tested, making tumor–normal expression one of MLIP-AS1’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where MLIP-AS1 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types MLIP-AS1 is over-expressed in tumor, although a few such as COAD and THCA show the opposite, repressed pattern.

KIRC, COAD, and THCA are the cancer types where MLIP-AS1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in MLIP-AS1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRC	All	III,IV	+0.012	.001	10	view →
COAD	Female	All	−0.052	<.001	7	view →
THCA	Female	All	−0.041	<.001	5	view →
HNSC	Male	III,IV	+0.017	.012	3	view →
CHOL	All	All	−0.075	.003	2	view →
BRCA	All	III,IV	−0.026	.020	2	view →
LUSC	All	All	+0.006	.004	2	view →
LIHC	All	All	+0.124	.023	1	view →
LIHC	Male	III,IV	−0.052	.008	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 9 strongest of 8 lineages.

MLIP-AS1–KIRC

Open the KIRC breakdown →