Across TCGA pan-cancer cohorts, MKRN7P Mutation is linked to patient survival in 4 of 34 cancer types, making it a survival-associated MKRN7P data layer compared with 19 for mass-spec protein.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where higher MKRN7P Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated MKRN7P expression acts as an unfavorable survival marker, although some lineages such as OV show a favorable association.

HNSC, OV, and COAD are the cancer types where MKRN7P Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
HNSC	OS	Median	All	0.155	0.685	.011	27	view →
OV	OS	Median	All	0.671	0.322	.015	24	view →
COAD	DFS	Median	All	0.035	0.791	<.001	15	view →
LIHC	OS	Median	All	0.098	0.774	.001	6	view →

Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

Exploration

Same gene, other analysis: MKRN7P tumor-vs-normal RNA expression · all MKRN7P data types