MKRN5P

RNA & survival
SurvivalRNAKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, MKRN5P RNA is linked to patient survival in 21 of 34 cancer types, making it the most broadly survival-associated MKRN5P data layer.

The strongest signal is observed in kidney chromophobe (KICH), where higher MKRN5P RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated MKRN5P expression acts as an unfavorable survival marker, although some lineages such as HNSC and LIHC show a favorable association.

KICH, HNSC, and KIRC are the cancer types where MKRN5P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
KICHDFSMedianIII,IV0.3220.942.00282view →
HNSCDFSQuartileAll0.4630.247<.00149view →
KIRCDFSMedianAll0.5370.680.00339view →
LUSCDFSMedianIII,IV0.5080.786<.00135view →
LIHCOSTertileII,III,IV0.8730.671.00531view →
LAMLDFSMedianAll0.5530.241.00130view →
ACCOSQuartileIV0.8900.428.00629view →
SKCMOSMedianAll0.4160.275<.00124view →
PAADOSQuartileAll0.5830.312.00621view →
KIRPOSMedianIII,IV0.8000.531.02918view →
DLBCOSMedianAll0.5590.957.00916view →
GBMOSQuartileAll0.5960.213<.00112view →
Pink = unfavorable, green = favorable. Showing the 12 strongest of 21 lineages.

Exploration