MKRN4P

Across TCGA pan-cancer cohorts, MKRN4P RNA is linked to patient survival in 25 of 34 cancer types, making it the most broadly survival-associated MKRN4P data layer.

The strongest signal is observed in rectum adenocarcinoma (READ), where higher MKRN4P RNA is associated with better disease-free survival. In most high-consensus cancer types, elevated MKRN4P expression acts as an unfavorable survival marker, although some lineages such as READ and ACC show a favorable association.

READ, OV, and ACC are the cancer types where MKRN4P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
READ	DFS	Tertile	All	0.916	0.758	.001	61	view →
OV	OS	Median	All	0.276	0.367	.001	44	view →
ACC	DFS	Quartile	III,IV	0.612	0.187	.006	33	view →
KIRP	DFS	Tertile	III,IV	0.518	0.838	.007	32	view →
BRCA	OS	Median	II,III,IV	0.418	0.658	<.001	26	view →
BLCA	OS	Quartile	IV	0.671	0.343	<.001	26	view →
LGG	DFS	Median	All	0.670	0.795	<.001	25	view →
ESCA	OS	Median	III,IV	0.699	0.403	.001	24	view →
UCEC	OS	Tertile	All	0.840	0.907	.016	22	view →
THCA	DFS	Tertile	III,IV	0.976	0.827	.018	9	view →
MESO	OS	Median	III,IV	0.307	0.708	.014	9	view →
KICH	DFS	Median	All	0.770	0.974	.004	9	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 25 lineages.

MKRN4P–READ (DFS)

Open the READ breakdown →