MKRN3

Across TCGA patient cohorts, MKRN3 RNA expression is significantly associated with the protein abundance of many other proteins, with 13,047 significant associations in total. GBM shows the largest number of these associations.

The most reproducible MKRN3-associated proteins across cancer lineages are TPX2_S486, XPO5, and SMARCD1. Each is linked with MKRN3 in more than 4 cancer types. Because this analysis shows association rather than direction, both MKRN3-to-partner and partner-to-MKRN3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, MKRN3 versus TPX2_S486 in HNSC, with a Pearson correlation of 0.37.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (MKRN3→partner) and Y-score (partner→MKRN3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	TPX2_S486 →	+0.769	+0.984	<.001	<.001	3	5
HNSC	XPO5 →	+0.418	+1.044	.001	<.001	3	5
GBM	SMARCD1 →	+0.328	+0.717	<.001	<.001	3	5
LSCC	UBXN7 →	+0.384	+0.925	.004	.004	3	4
HNSC	DDX47 →	+0.343	+0.702	<.001	<.001	3	4
GBM	ETFDH →	-0.346	-0.579	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,047 associations by consensus.

MKRN3 vs TPX2_S486 — HNSC

Explore this scatter interactively →