MKRN3

Across TCGA patient cohorts, MKRN3 protein abundance is significantly associated with the RNA expression of many other genes, with 904 significant associations in total. GBM shows the largest number of these associations.

The most reproducible MKRN3-associated genes across cancer lineages are TSPO, TRMU, and EHD4. Each is linked with MKRN3 in more than 1 cancer types. Because this analysis shows association rather than direction, both MKRN3-to-partner and partner-to-MKRN3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, MKRN3 versus TSPO in BRCA, with a Pearson correlation of 0.82.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MKRN3→partner) and Y-score (partner→MKRN3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	TSPO →	+0.900	+1.198	.002	.004	3	1
BRCA	TRMU →	+0.653	+1.346	.007	.001	3	1
BRCA	EHD4 →	+0.486	+1.198	.005	.004	3	1
BRCA	ZNF574 →	+0.445	+1.198	.008	.004	3	1
BRCA	MAP7D1 →	+0.988	+1.637	.002	.006	3	1
BRCA	FLVCR2 →	+0.706	+1.198	.007	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 904 associations by consensus.

MKRN3 vs TSPO — BRCA

Explore this scatter interactively →