MKRN3

Across TCGA cell cohorts, MKRN3 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,027 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible MKRN3-associated GO terms across cancer lineages are RNA catabolic process, Regulation of mRNA catabolic process, and RISC complex assembly. Each is linked with MKRN3 in more than 10 cancer types. Because this analysis shows association rather than direction, both MKRN3-to-partner and partner-to-MKRN3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA catabolic process grouped by MKRN3-low versus MKRN3-high in LUNG_NSCLC_LUSC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MKRN3→partner) and Y-score (partner→MKRN3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	RNA catabolic process →	+0.066	+2.802	<.001	.009	3	11
STOMACH	Regulation of mRNA catabolic process →	+0.063	+1.970	.002	.007	3	9
STOMACH	RISC complex assembly →	+0.123	+2.390	.002	<.001	3	9
CNS	Nucleic acid catabolic process →	+0.038	+1.034	.001	<.001	3	9
OESOPHAGUS	Establishment of RNA localization →	+0.088	+2.182	.003	.001	2	10
BREAST	Regulation of mRNA stability →	+0.043	+1.450	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,027 associations by consensus.

RNA catabolic process by MKRN3 expression — LUNG_NSCLC_LUSC

Explore this box plot interactively →