MKLN1

Across TCGA patient cohorts, MKLN1 protein abundance is significantly associated with the RNA expression of many other genes, with 11,303 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible MKLN1-associated genes across cancer lineages are HILPDA, PUS7, and NUP205. Each is linked with MKLN1 in more than 5 cancer types. Because this analysis shows association rather than direction, both MKLN1-to-partner and partner-to-MKLN1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, MKLN1 versus HILPDA in GBM, with a Pearson correlation of 0.31.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MKLN1→partner) and Y-score (partner→MKLN1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	HILPDA →	+1.019	+0.149	.002	<.001	3	6
HNSC	PUS7 →	+0.855	+0.189	<.001	<.001	3	6
BRCA	NUP205 →	+0.792	+0.205	<.001	<.001	3	6
HNSC	RINT1 →	+0.806	+0.184	.002	<.001	3	5
OV	METTL2B →	+0.561	+0.202	.005	.007	3	5
HNSC	SSBP1 →	+0.658	+0.167	.003	.001	2	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,303 associations by consensus.

MKLN1 vs HILPDA — GBM

Explore this scatter interactively →