MISP3

Across TCGA patient cohorts, MISP3 RNA expression is significantly associated with the protein abundance of many other proteins, with 14,681 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible MISP3-associated proteins across cancer lineages are MISP3_S91, CC2D1A, and MISP3_S18. Each is linked with MISP3 in more than 8 cancer types. Because this analysis shows association rather than direction, both MISP3-to-partner and partner-to-MISP3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, MISP3 versus MISP3_S91 in BRCA, with a Pearson correlation of 0.73.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (MISP3→partner) and Y-score (partner→MISP3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	MISP3_S91 →	+1.010	+1.405	<.001	<.001	3	9
OV	CC2D1A →	+0.420	+0.882	<.001	<.001	3	7
BRCA	MISP3_S18 →	+1.911	+2.098	<.001	<.001	3	7
HNSC	LLGL2 →	+0.469	+0.837	<.001	.003	3	6
BRCA	PTPN2 →	-0.327	-1.281	.001	<.001	3	6
LUAD	MISP3_S208 →	+1.020	+0.890	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,681 associations by consensus.

MISP3 vs MISP3_S91 — BRCA

Explore this scatter interactively →