Across TCGA patient cohorts, MIRLET7BHG mutation is significantly associated with the total protein of many other genes, with 13 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible MIRLET7BHG-associated genes across cancer lineages are p62 Lck ligand, p27_pT157, and Tuberin. Each is linked with MIRLET7BHG in more than 1 cancer types. Because this analysis shows association rather than direction, both MIRLET7BHG-to-partner and partner-to-MIRLET7BHG results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MIRLET7BHG→partner) and Y-score (partner→MIRLET7BHG) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	p62 Lck ligand →	+0.541	+3.179	.001	.010	3	2
UCEC	p27_pT157 →	-0.080	-3.156	.008	.018	3	1
UCEC	Tuberin →	+0.415	+3.321	.003	.010	3	1
UCEC	VHL →	-1.176	-3.169	<.001	.018	3	1
UCEC	Collagen-VI →	-0.339	-3.156	.001	.018	3	1
UCEC	C-Raf →	+0.206	+3.321	.005	.010	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 13 associations by consensus.

Exploration

MIRLET7BHG survival (RNA) · tumor vs normal (RNA) · all MIRLET7BHG data types