MIR9-3HG

Across TCGA pan-cancer cohorts, MIR9-3HG RNA is linked to patient survival in 22 of 34 cancer types, making it the most broadly survival-associated MIR9-3HG data layer.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where higher MIR9-3HG RNA is associated with better disease-free survival. In most high-consensus cancer types, elevated MIR9-3HG expression acts as an unfavorable survival marker, although some lineages such as HNSC and SKCM show a favorable association.

HNSC, KIRP, and SKCM are the cancer types where MIR9-3HG RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
HNSC	DFS	Median	All	0.752	0.637	<.001	143	view →
KIRP	OS	Tertile	III,IV	0.241	0.666	.002	70	view →
SKCM	OS	Median	All	0.413	0.258	<.001	56	view →
LGG	OS	Median	All	0.534	0.361	<.001	54	view →
ACC	OS	Median	All	0.778	0.961	<.001	45	view →
KICH	OS	Median	All	1.000	0.705	.006	40	view →
CESC	DFS	Quartile	All	0.548	0.330	.004	36	view →
UCEC	DFS	Tertile	IV	0.970	0.528	.020	34	view →
UCS	DFS	Quartile	III,IV	0.438	0.071	.014	32	view →
THCA	DFS	Median	IV	0.950	0.471	.002	27	view →
THYM	DFS	Quartile	All	0.648	0.969	.007	24	view →
KIRC	DFS	Tertile	IV	0.624	0.217	.004	24	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 22 lineages.

MIR9-3HG–HNSC (DFS)

Open the HNSC breakdown →