MIR9-3HG

Across TCGA pan-cancer cohorts, MIR9-3HG RNA differs between tumor and matched normal tissue in 13 of 18 cancer types tested, making tumor–normal expression one of MIR9-3HG’s most consistent transcriptional readouts.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where MIR9-3HG RNA is more highly expressed in tumor relative to normal tissue. In most cancer types MIR9-3HG is over-expressed in tumor, although a few such as COAD and THCA show the opposite, repressed pattern.

HNSC, COAD, and THCA are the cancer types where MIR9-3HG tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in MIR9-3HG RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
HNSC	Male	All	+0.992	<.001	11	view →
COAD	All	II,III,IV	−0.197	<.001	10	view →
THCA	All	III,IV	−1.098	<.001	9	view →
KIRP	Female	All	−0.977	<.001	7	view →
LUSC	Female	All	+1.358	<.001	6	view →
BLCA	All	III,IV	+1.149	.007	6	view →
LIHC	Female	II,III,IV	+0.088	<.001	5	view →
LUAD	All	All	+0.672	<.001	4	view →
STAD	Female	III,IV	+0.549	.023	3	view →
READ	All	All	−0.237	.003	3	view →
KICH	Female	II,III,IV	+1.630	.030	2	view →
BRCA	All	III,IV	+0.707	.006	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 13 lineages.

MIR9-3HG–HNSC

Open the HNSC breakdown →